HEK 293 cells are commonly used for vector production of biopharmaceuticals, vaccines, and cell and gene therapies. The HEK 293 HCP Solution for Gyrolab consists of the HEK 293 HCP Assay Reagent Set for Gyrolab ordered from Cygnus Technologies and the Gyrolab Bioaffy™ 1000 HC Assay Toolbox.

HEK 293 HCP Solution for Gyrolab for the detection of HEK 293 host cell protein (HCP) impurities offers the following benefits:

  • Automated workflows – reduced manual operations
  • Broad dynamic range – over three logs
  • Fast turnaround time – 96 data points in 75 minutes
  • High throughput – up to 960 data points in a working day

The HEK 293 HCP Assay Reagent Set for Gyrolab is derived from the same antibodies and antigen used in the Cygnus 3rd Generation Resupply HEK 293 HCP ELISA kit, (Cygnus Cat. no. F650S*). The reagents are "generic” in the sense that they are intended to react with essentially all the HCPs that could contaminate the product independent of the purification process. 

This simple to use, high throughput, and semi-quantitative assay can be used to aid in optimal purification process development, process control, routine quality control, and product lot release. 

GRAPH: Gyrolab and ELISA assays of viral vector downstream bioprocessing samples show comparable results. 

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Gyrolab ordering information

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Gyrolab Bioaffy 1000 HC Assay Toolbox

Contains 1 CD and all buffers and consumables needed to generate 96 data points (1 CD). P0020667

Gyrolab Bioaffy 1000 HC Assay Toolbox CD50

Contains 50 CDs and all buffers and consumables needed to generate 4800 data points (50 CDs). P0020668

Gyrolab HCP Sample Dilution Buffer

Extra sample dilution buffer for Gyrolab Bioaffy 1000 HC Assay Toolbox. P0020670

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Cygnus ordering information

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HEK 293 HCP Assay Reagent Set for Gyrolab

Contains anti-HEK 293 HCP capture and detection reagents and HEK 293 HCP antigen concentrate. Quantities enough to generate 96 data points (1 CD). G650S-1

*The original HEK 293 HCP Assay Reagent Set for Gyrolab® (G650S) from Cygnus Technologies will no longer be available due to its capture and detection antibody stock depletion. Should you have any questions or require further assistance regarding product G650S, please contact techsupport@cygnustechnologies.com or visit Cygnus Technologies.

 

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