Gyrolab mouse and human cytokine kits accelerate biotherapeutic development

Precise and robust fit-for-purpose pharmacodynamic and safety biomarker assays are needed to support the development of biotherapeutics in preclinical and clinical studies. Gyrolab mouse and human cytokine assays provide fast, fully automated, high sensitivity, and reliable biomarker assay performance with wide dynamic ranges and low sample volumes to meet the needs of regulated environments.

Gyrolab Mouse Cytokine Kits and Gyrolab Human Cytokine Kit Reagents enable the quantification of IL-4, IL-6, IL-10, IFN-gamma and TNF-alpha in mouse and human serum down to low pg/mL levels using the Gyrolab Bioaffy™ 4000 CD. Biomarker quantification using Gyrolab platform positively impacts productivity in the development of therapeutics.

  • Get results faster with minimal hands-on time
    90-minute automated run times 
    Maximize laboratory productivity
  • Rely on reproducible results in regulated environments
    Reproducible, high-quality data across operators and instruments over long time periods 
    Software designed for 21 CFR Part 11 compliance
  • Save operator time with fewer dilutions and re-runs 
    Low pg/mL sensitivity, 3-4 logs dynamic range
    High matrix tolerance 
  • Biomarker assays run precisely using Gyroplex® panels
    Independent assays with no opportunity for crosstalk
    Straightforward validation of single-analyte assays

 

Gyrolab mouse and human cytokine kits accelerate biotherapeutic development
Standard curves for all five cytokines run sequentially in a 5CD Gyroplex format
Standard curves Human Cytokine Reagent Sets

Typical standard curves: Gyrolab mouse (left) and human (right) cytokines

Standard curves for each Mouse Cytokine Kit (IL-4, IL-6, IL-10, IFN-gamma, and TNF-alpha), left panel, and each Human Cytokine Kit Reagent set (IL-4, IL-6, IL-10, IFN-gamma, and TNF-alpha), right panel, were run sequentially on a Gyrolab xPand in a 5-CD Gyroplex format, with each assay on a separate Gyrolab Bioaffy 4000 CD

Don't see your assay here?

Gyrolab assay protocols are available for more cytokines and other biomarkers, providing assay conditions to jump start assay development. In addition, development of your own assay is always possible on the Gyrolab platform open system.

Browse Gyrolab Mouse Cytokine Kits

Browse Gyrolab Human Cytokine Kit Reagents

Download Application Note: Selective and robust biomarker quantification using Gyrolab human cytokine kit reagents

Selective and robust biomarker quantification using Gyrolab human cytokine kit reagents Application Note

 

Want to learn more? Speak to our scientists about your biomarker assay needs.

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