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    Gyrolab Systems

Gyrolab is an automated immunoassay platform for biopharmaceutical labs, built to run ligand binding assays with high reproducibility and minimal sample and reagent use. Using nanoliter-scale centrifugal microfluidics and a flow-through affinity format, Gyrolab applies a miniaturized ELISA approach inside a rotating disc, helping labs increase throughput while reducing manual work. Gyrolab is an open platform and can run with Gyrolab kits, reagents from any supplier, or your own reagents.  

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Gyrolab systems

How Gyrolab technology enhances automated immunoassays 

Gyrolab technology is designed to control how liquids move, interact and bind at the nanoliter scale. By combining centrifugal microfluidics with a flow-through affinity format, the platform creates rapid turnaround with highly consistent assay results and minimal manual influence.

Defined volumes, controlled residence time and automated execution reduce variability between runs, users and labs. Detection is performed using laser-induced fluorescence, supporting reliable signal generation across a broad dynamic range. 

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How Gyrolab speeds up your workflow

How Gyrolab speeds up your workflow

Short assay turnaround time means results are generated in about an hour once the run begins. Combined with a wide working concentration range, more samples remain within quantification limits without repeated dilution or reanalysis. Fewer reruns and reduced manual intervention translate into faster time to data delivery and more predictable project timelines.



How microfluidic discs power Gyrolabs nanoliter precision

How microfluidic discs power Gyrolabs nanoliter precision

Gyrolab microfluidic discs use centrifugal force, capillary action and hydrophobic barriers to guide samples and reagents through precisely defined structures. These physical controls determine exact nanoliter volumes and timing, removing much of the variation introduced by manual pipetting and incubation in plate-based ELISA. The result is predictable assay execution using significantly less sample and reagent. 

How flow-through affinity technology increases reproducibility in Gyrolab

How flow-through affinity technology increases reproducibility in Gyrolab

Instead of static incubation, Gyrolab uses a flow-through affinity format where samples pass through an affinity column under controlled conditions. Short, defined time on column limits non-specific binding and reduces matrix effects in biological samples. This approach supports reproducible binding behavior and consistent data generation, even across different workflows and environments.

Introducing Gyrolab® xPlore™ and Gyrolab® xPand

Accelerate bioanalytical workflows with precision, flexibility, and reliable performance

The Gyrolab platform helps scientists simplify immunoassay workflows and consistently generate high-quality data with minimal hands-on time. Whether you’re scaling assays, increasing throughput, or building robust methods for regulated environments, Gyrolab xPlore and Gyrolab xPand give you the flexibility and performance to do so efficiently. 

Gyrolab xPlore

Gyrolab xPlore

Reliable automation for everyday immunoassays

Gyrolab xPlore brings automated immunoassays into a compact, easy-to-use format. Designed as an accessible entry point to the Gyrolab platform, it helps you reduce manual work while maintaining consistent, high-quality data.

Whether you're developing methods or running routine assays, Gyrolab xPlore supports efficient workflows with reliable performance. Walkaway automation allows you to set up, run, and analyze assays with minimal intervention — freeing up time for other tasks.

What this means for your lab:

  • Run assays with less hands-on time and fewer manual steps

  • Fit automated workflows into labs with limited space

  • Move easily between method development and routine analysis

Download Product information sheet

Download Product information sheet

Gyrolab xPlore delivers high precision immunoassay data with great reproducibility.

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Gyrolab xPand

Gyrolab xPand

High-throughput automation for demanding workflows

Gyrolab xPand is designed for labs managing large sample volumes and tight timelines. Automated plate handling and batch processing help you scale your immunoassay workflows while maintaining consistent, reproducible results.

Built for high-throughput environments, Gyrolab xPand reduces manual intervention and supports reliable performance across runs, operators, and sites. It is well-suited for regulated workflows where traceability, consistency, and efficiency are critical.

What this means for your lab:

  • Process large sample volumes with minimal hands-on time

  • Reduce variability and risk of manual error

  • Generate consistent, high-quality data in regulated environments

Download Product information sheet

Download Product information sheet

Gyrolab xPand with temperature control ensures high reproducibility among the five CDs in one run.

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Analytical areas

Automated immunoassays are used across bioanalysis and bioprocessing wherever results must be generated quickly, across wide concentration ranges and with limited manual intervention. Gyrolab is designed for these environments, supporting workflows such as process optimization, host cell protein (HCP) quantification and bioanalytical testing where reproducibility and dynamic range are critical.

  • PK and TK

    Automated nanoliter-scale assays deliver precision, sensitivity, and speed needed for regulatory-ready PK data, even when sample volumes are limited.
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  • Immunogenicity

    Fast anti-drug antibody (ADA) workflows and software modules simplify screening and drug-specific assays while reducing manual steps.
    View Immunogenicity

  • Biomarkers

    Highly sensitive, fit-for-purpose pharmacodynamic and safety biomarker assays deliver reproducible, low-volume results with minimal hands-on time.
    View Biomarker

  • Affinity

    In-solution affinity measurements provide accurate KD values quickly, and confirm reagent quality. 
    View Affinity

  • Impurity analysis

    Automation delivers rapid, routine quantification of product and process impurities, ensuring critical quality attributes and process controls are maintained at every stage. 
    View Impurity Analysis

  • Titer analysis

    High matrix tolerance and minimal dilution steps enable fast titer quantification at every stage of cell line and process development. 
    View Titer Analysis

Comparative analysis

Ligand binding assays remain a cornerstone of bioanalysis, with ELISA still widely used as a standard approach. At the same time, increasing demands on throughput, matrix tolerance and workflow efficiency have driven the adoption of more automated formats.

Compared with traditional ligand binding assays, the Gyrolab platform is designed to reduce manual steps and shorten development timelines. Flow-through microfluidics and controlled residence time improve matrix tolerance, while automated execution supports faster assay development, in some cases reducing timelines from weeks to days.

 

Compared with traditional ligand binding assays, the Gyrolab platform is designed to reduce manual steps and shorten development timelines. Flow-through microfluidics and controlled residence time improve matrix tolerance, while automated execution supports faster assay development, in some cases reducing timelines from weeks to days.
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Compliance & data integrity

Regulated workflows require confidence that data is traceable, controlled and ready for inspection. Gyrolab software supports 21 CFR Part 11 requirements, with full audit trails, controlled user access and electronic signatures. Results can be exported to laboratory information management systems through built-in LIMS integration, supporting structured data handling across organizations.

High reproducibility also simplifies method transfer between R&D, QC, and external CRO partners, helping maintain consistency as assays move across teams and sites.



Technical resources and peer-reviewed publications

Gyrolab Systems Brochure

Gyrolab Systems Brochure

An overview of the Gyrolab immunoassay platform, including Gyrolab xPand and Gyrolab xPlore systems

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Gyrolab vs ELISA

Gyrolab vs ELISA

A case study comparing Gyrolab and ELISA, highlighting broader dynamic range, higher throughput and reduced effort in regulated bioanalysis.

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FAQ section

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