Bioprocess (1)

Go Beyond your Expectations for Bioprocess Titer and Impurity Analysis

Transform the performance and productivity of bioprocessing immunoassays: miniaturize, automate, and analyze faster.

Impurity and titer analysis during bioprocess development that is rapid and precise using Gyrolab® immunoassays accelerates workflows and increases throughput. The microfluidic immunoassays utilizing the Bioaffy CD format are fully automated and are completed in about one hour for high throughput sample analysis that streamlines workflows and provides data for time-relevant decision making.

Wide assay dynamic ranges of 3-4 logs means high pass rates on the first run and reduced sample dilution requirements, saving analyst time.  The low sample volume requirements of <10 µL conserves precious samples and reagents, to generate more data with less sample in less time.

Skip assay development with Gyrolab Kits 

Gyrolab ready-to-use kits for host cell protein (HCP) impurity analysis and the presence of other impurities such as protein A, biotherapeutic product titer kits for human IgG, and gene therapy adeno-associated viral (AAV) vector or lentiviral vectors, have been extensively tested for reliable performance and precise results, empowering bioanalytical QC Engineers to set-up immunoassays quickly and focus on what matters: robust results. 

Read how our customers define success

Scientists at Sanofi have successfully implemented Gyrolab immunoassay system as a reliable platform for high-throughput HCP analysis. Read more in the Case Study, Host-Cell Protein Analysis to Support Downstream Process Development

Read the article

For more information, see these bioprocess development applications:

    Gyrolab Systems
    Gyrolab technology reduces manual labor, assay development time, time to result and material consumption -and it improves workflow efficiency. 
    [Brochure]

    Gyrolab Kits, CDs and Rexxip Buffers
    Gyrolab Kits, CDs and Rexxip Buffers - Designed for best results 
    [Brochure]

    Gyrolab CDs
    Select the appropriate CD for a specific immunoassay based on the required dynamic range, the analyte concentration, the quality of reagents and the assay format.  
    [Product information sheet]

    Gyrolab xPlore
    Gyrolab xPlore single-CD system automates high performance immunoassays throughout biopharma development and production. 
    [Product information sheet]

    Gyrolab xPand
    Gyrolab xPand five CD system optimizes immunoassay development, processing and performance in your laboratory. 
    [Product information sheet]

    Host-Cell Protein Analysis to Support Downstream Process Development
    Sanofi scientists present the successful implementation of the Gyrolab immunoassay system as a reliable platform for high-throughput HCP analysis, in combination with a robotic liquid handling system. The results were comparable to their gold-standard ELISA method. 
    [Case Study]

    Overcoming Limitations of ELISAs in Process-related Impurity Testing
    In this webinar, Utku Hasbay at Takeda Pharmaceuticals presented transfer of an HCP ELISA to Gyrolab® to expand the dynamic range with a 2 hour assay time 
    [Webinar]

    Accelerating bioprocess workflows with microfluidic immunoassay-based parallel impurity analysis
    Maximize performance and productivity in your bioprocess workflows for biologics Gyrolab® immunoassays deliver rapid turnaround to support data-driven decision-making 
    [Poster]

    High Throughput Platform and Automated Sample Preparation for Host Cell Protein Analysis to Support Downstream Process Development
    Speaker: Suzana Petrovic Analytical Scientist Sanofi. Learn how a high-throughput immunoassay platform supported accelerated bioprocess HCP assay development utilizing Gyrolab xP and CHO-HCP E3G kit. 
    [Webinar]