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Product number: P0020455
Gyrolab Mixing CD 96 integrates and automates sample pretreatment into the assay workflow made possible by Gyrolab platforms. Automating sample pretreatment and immunoassay workflow at nanoliter scale creates a number of advantages including:
VIDEO: See what happens inside Gyrolab Mixing CD 96 when used for ADA analysis.
In the Gyrolab automated Protein A method for detection of leached MabSelect SuRe™ ligands, samples are acidified in Gyrolab Mixing CD 96 to dissociate Protein A-IgG complexes. The amount of Protein A is then determined by a sandwich immunoassay.
For anti-drug antibody (ADA) analysis in preclinical or clinical serum samples, the mixing function in the Gyrolab Mixing CD 96 can be used to automate sample pre-treatment for acid dissociation of the interfering biotherapeutic. Miniaturization simplifies detection of anti-drug antibodies, even in the presence of a high drug concentration. The individual microstructures integrate the acid dissociation process to minimize variation between samples, while dedicated Gyrolab ADA software supports assay development and validation for cut point determination, screening, and confirmatory analysis.