Gyrolab Resources

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October 30, 2019
11:00 am Eastern Daylight Time (New York, GMT-04:00)

A Gyrolab Assay for the Quantitation of Free Complement Protein C5a in Human Plasma


Mark Dysinger, M.S., Development Scientist III
Alexion Pharmaceuticals

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Quantitation of active GLP-1
GLP-1 is a gut hormone that is secreted in response to food intake, affecting both metabolism and weight. Since endogenous levels of GLP-1 are typically less than 5 pM in diabetes and obesity, the chosen method must have high sensitivity. Gyros Protein Technologies has developed an automated immunoassay for human active GLP-1 using commercially available reagents. 
[Application Note]

Maximizing productivity in biopharmaceutical research and clinical development
Three case studies are presented: "Obtaining an entire PK profile form a single mouse", "Earlier and more sensitive detection of drug-induced kidney toxicity in preclinical studies" and "Ramping up Phase II/III PK studies to meet critical deadlines". 
[Application Note]

Quantitation of Host Cell Protein Impurities
Gyrolab HCP assays deliver high precision results over a broad dynamic range, minimizing repeat analysis in bioprocess development and production. 
[Application Note]

Immunoassays to maximize productivity in bioprocess development
Gyrolab systems meet the needs of many biopharmaceutical companies that apply immunoassays to bioanalysis throughout bioprocess development. Gyrolab immunoassay platform addresses bottlenecks and delays by providing rapid assay development time, automation, high throughput, and a broad dynamic range that minimizes dilutions and repeats.  
[Application Note]

Quantitation of Antibody-Drug Conjugates
Using Gyrolab systems, a generic IgG assay and an assay to measure payloads of ADCs can quickly be developed in parallel. 
[Application Note]