Application Note
Accelerate reliable screening during drug discovery with high-throughput peptide purification
The absence of impurities in peptides, synthesized via SPPS, is vital for reliable assay results. However, especially in drug discovery screenings (number of peptides > 24), potentially low-purity crude peptides are often used because parallel purification with chromatography is not possible. We overcome this bottleneck by parallelization of the orthogonal PurePep® EasyClean (PEC) purification technology to a 96 well-plate format.
What you will learn about
- access massive parallel purification of peptides with PEC in a 96-well filter plate format
- a one-method-fits-all procedure that creates PEC-grade peptides with an average purity of 86%
- improving assay reliability through absence of peptide-related impurities