Gyros Protein Technologies

Recorded Webinar from April 16, 2019

Development of sensitive ADA assays using automated acid dissociation in Gyrolab® Mixing CD 96


Measuring Anti-Drug-Antibody (ADA) levels is an important part of developing new biologics. The clinical implication of the presence of anti-drug-antibodies in treated patients may include allergic reactions, immune complex toxicity, autoimmune reactions and reduction of efficacy.

Recently regulatory agencies have lowered the sensitivity requirement for ADA detection, from 250-500 ng/mL to 100 ng/mL. To reach such sensitivity levels without affecting the assay drug tolerance, sample pre-treatment steps may be necessary. Gyrolab ADA Solution streamlines ADA assay workflows and automates acid dissociation steps to improve sensitivity and drug tolerance of ADA assays while reducing variability and saving time.

In this webinar, Sarah Collomb from Novimmune SA will present an example of the development of a pre-clinical ADA assay using Gyrolab Mixing CD 96.

John Chappell, Application & Service Director
EMEA and Asia Pacific
Gyros Protein Technologies

Sarah Collomb, Research Assistant
Novimmune SA

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