De Leon-Rodriguez L.M. et al. Acta Biomaterialia Volume 47, 1 January 2017, Pages 40–49.2016
Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic Beta-hairpins
Danelius E. et al. Org. Biomol. Chem., 2016,14, 10386-10393.2016
The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism Cell.
Wootten D. et al. Cell. 2016 Jun 16; 165(7): 1632-1643.2016
Modular peptide amphiphile micelles improve an antibody-mediated immune response to Group A Streptococcus.
Barrett J.C. et al. ACS Biomater. Sci. Eng.2016
Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo.
Stone T.A. et al. Biochemistry, 2016, 55 (40), pp 5772–5779.2016
Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation.
Elbassal E.A. et al. The Journal of Physical Chemistry. B, 120(1), 59-68.2016
Baltikinin: A New Myotropic Tryptophyllin-3 Peptide Isolated from the Skin Secretion of the Purple-Sided Leaf Frog, Phyllomedusa baltea.
Shi D. et al. Toxins, 8(7), 213.2016
Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses.
Galant N.J. et al. Scientific Reports, 6, 25080.2016
Serum Stability and Affinity Optimization of an M2 Macrophage-Targeting Peptide (M2pep).
Ngambenjawong C. et al. Theranostics, 6(9), 1403-1414.2016
Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor.
Shi D. et al. Toxins, 8(5), 144.2016
Topical Delivery of Protein and Peptide Using Novel Cell Penetrating Peptide IMT-P8.
Gautam A. et al. Scientific Reports, 6, 26278.2016
Sequence, structure, and cooperativity in folding of elementary protein structural motifs.
Lai J.K. et al. Proceedings of the National Academy of Sciences of the United States of America, 112(32), 9890-9895. 2015
An Unprecedented alteration in mode of action of IsCT resulting its translocation into bacterial cytoplasm and inhibition of macromolecular syntheses.
Tripathi J.K. et al. Scientific Reports, 5, 9127. 2015
Biocompatibility and Characterization of a Peptide Amphiphile Hydrogel for Applications in Peripheral Nerve Regeneration.
Black K.A. et al. Tissue Engineering. Part A, 21(7-8), 1333-1342. 2015
Identification and Functional Analysis of a Novel Tryptophyllin Peptide from the Skin of the Red-eye Leaf Frog, Agalychnis callidryas.
Wang R. et al. International Journal of Biological Sciences, 11(2), 209-219. 2015
Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.
Rodriguez M.C. et al. Biochemistry, 54(29), 4462-4474. 2015
The frequency of naive and early-activated hapten-specific B cell subsets dictates the efficacy of a therapeutic vaccine against prescription opioid abuse.
Laudenbach M. et al. Journal of Immunology (Baltimore, Md.?: 1950), 194(12), 5926-5936. 2015
Phage display-guided nanocarrier targeting to atheroprone vasculature.
Hofmeister L.H. et al. ACS Nano, 9(4), 4435-4446. 2015
A Peptide Mimicking a Region in Proliferating Cell Nuclear Antigen Specific to Key Protein Interactions Is Cytotoxic to Breast Cancer.
Smith S. J. et al. Molecular Pharmacology, 87(2), 263-276. 2015
Hydrophobic Blocks Facilitate Lipid Compatibility and Translocon Recognition of Transmembrane Protein Sequences.
Stone T. A. et al. Biochemistry, 54(7), 1465-1473. 2015
AaeAP1 and AaeAP2: Novel Antimicrobial Peptides from the Venom of the Scorpion, Androctonus aeneas: Structural Characterisation, Molecular Cloning of Biosynthetic Precursor-Encoding cDNAs and Engineering of Analogues with Enhanced Antimicrobial and Anticancer Activities.
Du Q. et al. Toxins, 7(2), 219-237. 2015
Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.
Design, Synthesis and Biological Evaluation of 68Ga-DOTA-PA1 for Lung Cancer: A Novel PET Tracer for Multiple Somatostatin Receptors Imaging
Liu F. et al. Mol Pharm. 2017 Dec 27. doi: 10.1021/acs.molpharmaceut.7b00963. Epub ahead of print.2017
Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia
Zhou J. et al. Oncotarget. 2017 Oct 20; 8(50): 87095–87106.2017
An MD2-derived peptide promotes LPS aggregation, facilitates its internalization in THP-1 cells, and inhibits LPS-induced pro-inflammatory responses
Tandon A., Harioudh M., Ishrat N. et al. Cell. Mol. Life Sci. (2018).2018
Effects of Proline-Rich Peptides of the Innate Immune System on Drug-Resistant Bacterial Strains
Zharkova M.S. et al. Medical Immunology (Russia)/ Meditsinskaya Immunologiya 2018, Vol. 20, 1, pp. 107-114.2018
An MRM-Based Cytokeratin Marker Assay as a Tool for Cancer Studies: Application to Lung-Cancer Pleural Effusions
Perzanowska A. et al. Prot. Clin. Appl., 1700084. Accepted Author Manuscript. doi:10.1002/prca.201700084.2018
Elucidation of the binding mode of the carboxyterminal region of peptide YY to the human Y2 receptor
Xu B. et al. Molecular Pharmacology January 24, 2018, mol.117.110627; DOI: https://doi.org/10.1124/mol.117.110627.2018
Development of a solid-phase traceless-Ugi multicomponent reaction for backbone anchoring and cyclic peptide synthesis
Jobin S., Beaumont C. & Biron E. Peptide Science, 2475-8817.DOI: 10.1002/pep2.24044.2018
Self-assembly of Filamentous Cell Penetrating Peptides for Gene Delivery
Xu D. et al. Peptide Self-Assembly. Methods in Molecular Biology, vol 1777. Humana Press, New York, NY.2018
Monoclonal antibody against the universal M2 epitope of influenza A virus
Feng M. et al. Appl Microbiol Biotechnol (2018)2018
Relative role(s) of leucine versus isoleucine in the folding of membrane proteins
Deber C.M. & Stone T.A. Peptide Science. 2018;e24075. 2018
Synthesis, antibacterial, and antibiofilm potential of human autophagy 16 polypeptide and analogues
Varnava K.G. et al. Peptide Science. 2018;e24076.2018
Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction
Klyachkin Y.M. et al. Stem Cell Rev and Rep (2018). 2018
Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV‐1 Integrase
Northfield S. et al. ChemMedChem. Accepted Author Manuscript.2018
Cisplatin-loaded hollow gold nanoparticles for laser-triggered release
Xiong C. et al. Cancer Nano (2018) 9: 6.2018
Quantification of hydrolyzed peptides and proteins by amino acid fluorescence
Allenspach M.D. et al. Peptide Science (2018) 110, e3113.2018
Rapid Bioorthogonal Chemistry Enables in Situ Modulation of the Stem Cell Behavior in 3D without External Triggers
Hao Y. et al. ACS Appl. Mater. Interfaces, 2018, 10 (31), pp 26016–26027.2018
Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex
Simms J. et al. iochemistry Article ASAP.2018
A liquid chromatography high-resolution mass spectrometry in vitro assay to assess metabolism at the injection site of subcutaneously administered therapeutic peptides
Esposito S. et al. Journal of Pharmaceutical and Biomedical Analysis Volume 159, 10 September 2018, Pages 449-458.2018
Peptide ligand-based ELISA reagents for antibody detection
Heyduk E. et al. Analytical Biochemistry, Available online 18 August 2018.2018
Lipophilicity prediction of peptides and peptide derivatives by consensus machine learning
Fuchs J-A. et al. Med. Chem. Commun., 2018, Advance Article.2018
Interaction of Insulin-Like Growth Factor-Binding protein 3 With Hyaluronan and Its Regulation by Humanin and CD44
Muterspaugh R. et al. Biochemistry, Just Accepted Manuscript, Publication Date (Web): September 5, 2018.2018
Selection and structural analysis of the NY25 peptide – A vaccine candidate from hemagglutinin of swine-origin Influenza H1N1
Khrustalev V. V. et al. Microbial Pathogenesis, Volume 125, December 2018, Pages 72-83.2018
Injectable Supramolecular Hydrogel/Microgel Composites for Therapeutic Delivery
Chen M.H. et al. Macromol. Biosci. 2018, 1800248. 2018
Rapid and low-cost multiplex synthesis of chemokine analogs
Paolini-Bertrand M. et al JBC Papers in Press. Published on October 10, 2018 as Manuscript RA118.004370.2018
Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis”
Veggiani G. et al. Protein Science. Accepted Author Manuscript.2018
Design of Y2 Receptor Selective and Proteolytically Stable PYY3–36 Analogues
Østergaard S. et al. J. Med. Chem. 2018, 61, 23, 10519-10530.2018
Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism
Mroz P.A. et al. Molecular Metabolism Available online 5 December.2018
Structure-activity relationships of the bacteriocin bactofencin A and its interaction with bacterial membrane
Bedard F., Fliss I., and Biron E. ACS Infect. Dis., Just Accepted Manuscript,Publication Date (Web): December 12.2018
Combined Antibacterial Effect In Vitro of Human Salivary Prolinerich Peptide P-F (43-61) and Cationic Antimicrobial Peptides
Zharkova M.S. et al. UDC 616-092.19.2018
Aerosol delivery of dry powder synthetic lung surfactant to surfactant-deficient rabbits and preterm lambs on non-invasive respiratory support
Walther F.J. et al. Gates Open Research, (version 1; referees: awaiting peer review)2019
Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth
Shah K.K. et al. bioRxiv, preprint first posted online Feb. 19.2019
Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel
Vasseur L. et al. Toxicon X. Available online 23 February 2019, 100010.2019
‘Messy’ Processing of χ-conotoxin MrIA Generates Homologues with Reduced hNET Potency
Ziegman R. et al. Mar. Drugs 2019, 17(3), 165.2019
NMR Characterization of Conformational Fluctuations and Non‐covalent Interactions of SUMO protein from Drosophila melanogaster (dSmt3)
Kaur A. et al. Proteins. Accepted Author Manuscript. 2019
Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels
Jin A.-H. et al. Biochemical Pharmacology, In Press, Accepted Manuscript.2019
Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor
Chambers C. et al. FEBS Lett. Accepted Author Manuscript. 2019
Effect of Processing and End Groups on the Crystal Structure of Polypeptoids Studied by Cryogenic Electron Microscopy at Atomic Length Scales
Jiang X. et al. Soft Matter, 2019, Accepted Manuscript.2019
Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens
Pedron C.N. et al. Bioorganic Chemistry,Available online 8 June 2019, 103038, In Press, Accepted Manuscript.2019
The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
Pedron C.N. et al. European Journal of Pharmaceutical Sciences, Available online 7 June 2019. In Press, Accepted Manuscript.2019
Hydrophobic matching of HIV-1 Vpu transmembrane helix-helix interactions is optimized for subcellular location
Gregory B.Cole and Simon Sharpe Biochimica et Biophysica Acta (BBA) - Biomembranes2019
Affinity‐triggered assemblies based on a designed peptide‐peptide affinity pair
Claudia S. M. Fernandes et al. Biotechnology Journal2019
Peptide-based efflux pump inhibitors of the small multidrug resistance protein from Pseudomonas aeruginosa
Chloe J Mitchell, et al. Antimicrobial Agents and Chemotherapy2019
The aspartimide problem persists: Fluorenylmethyloxycarbonyl‐solid‐phase peptide synthesis (Fmoc‐SPPS) chain termination due to formation of N‐terminal piperazine‐2,5‐diones
Samson, D et al. Journal of Peptide Science2019
Solid-Phase Zincke Reaction for the Synthesis of Peptide-4,4′-bipyridinium Conjugates